AMT All Breed Test

We have combined three of the most popular and most common inherited disease screenings into one product. Whether you have a pure breed, intentionally mixed breed, or a loveable "mutt".  This test will assist you in taking care of that furry family member.  The following are the three tests that are included in one price.

Degenerative Myelopathy Carrier Testing:

 Canine Degenerative Myelopathy (DM) is a devastating degenerative disease of the spinal cord that can progress rapidly and cause weakness in the hind limbs and eventually paraplegia among genotypically affected dogs.

 Symptoms:

Early Stages

• Progressive weakness of the hind limbs
• Worn nails
• Difficulty rising
• Stumbling
• Knuckling of the toes
• Scuffing hind feet
• Wearing of the inner digits of the rear paws
• Loss of muscle in the rear legs
• Tremors of the rear legs

Late Stages

• Persistent early stages
• Urinary and fecal incontinence
• Eventual front leg weakness from compensatory strain
• Mental stress and anxiety
• Pressure sores on boney prominences
• Inability to rise
• Muscle atrophy
• Poor hygiene - soiled appearance
• Pneumonia
• Depression
• Infection/sepsis
• Constipation
• Organ failure

 Uric Acid (Hyperuricosuria):

 Hyperuricosuria, or elevated uric acid level in the urine, is inherited as an autosomal recessive disorder and is characterized by the formation of bladder stones and occasional kidney stones.
Symptoms: 

• Straining and/or discomfort during urination
• Blood in the urine
• Passing only small amounts of urine
• Urine leakage accidents around your home
• Drinking and urinating more

 Multidrug Resistance (MDR1): 

 Multidrug Resistance 1 is inherited as an autosomal incomplete dominant disease. Dogs only need to inherit one copy of the MDR1 mutation to be at risk for sensitivity of certain drugs. Dogs with 2 copies of MDR1 can have more severe reactions.   Although this is more common in certain breeds all breeds may be affected.
Dogs that have a mutation in the MDR1 gene, which inhibits their ability to remove certain drugs from the brain and can lead up to a buildup of toxins, may have severe adverse reactions to some common drugs, including seizures, tremors, disorientation, blindness, lack of muscle control or even death.
Dogs may be sensitive to:

• Antibiotics such as erythromycin and rifampin
• Anti-cancer drugs such as doxorubicin, vinblastine and vincristine
• Anti-diarrheal drugs such as loperamide (Imodium®)
• Certain parasite-control products such as ivermectin (in high doses), milbemycin, moxidectin and selamectin
• Pain medications such as butorphanol
• Tranquilizers/sedatives such as acepromazine

Please inquire about other testing that may be available for your specific breeds.  We have testing available for over 200 dog breeds.